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Journal article

The early whole-blood transcriptional signature of dengue virus and features associated with progression to dengue shock syndrome in Vietnamese children and young adults.

Abstract:

Dengue is a pantropic public health problem. In children, dengue shock syndrome (DSS) is the most common life-threatening complication. The ability to predict which patients may develop DSS may improve triage and treatment. To this end, we conducted a nested case-control comparison of the early host transcriptional features in 24 DSS patients and 56 sex-, age-, and virus serotype-matched uncomplicated (UC) dengue patients. In the first instance, we defined the "early dengue" profile. The tran...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.01224-10

Authors


Birren, BW More by this author
Lennon, NJ More by this author
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Journal:
Journal of virology
Volume:
84
Issue:
24
Pages:
12982-12994
Publication date:
2010-12-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:77221733-f481-4f80-a5d6-67a8a06f028c
Source identifiers:
98257
Local pid:
pubs:98257

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