Journal article
A Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesis.
- Abstract:
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The membrane occupation and recognition nexus protein 1 (MORN1) is highly conserved among apicomplexan parasites and is associated with several structures that have a role in cell division. Here we dissected the role of MORN1 using the relatively simple budding process of Toxoplasma gondii as a model. Ablation of MORN1 in a conditional null mutant resulted in pronounced defects suggesting a central role for MORN1 in apicoplast segregation and in daughter cell budding. Lack of MORN1 resulted i...
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(pdf, 11.3MB)
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- Publisher copy:
- 10.1371/journal.pone.0012302
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Bibliographic Details
- Journal:
- PloS one
- Volume:
- 5
- Issue:
- 8
- Pages:
- e12302
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1932-6203
- Source identifiers:
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246600
Item Description
- Language:
- English
- Keywords:
- UUID:
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uuid:770d2831-d805-4215-bad6-6d684103ad17
- Local pid:
- pubs:246600
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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