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Oxygen consumption dynamics in steady-state tumour models.

Abstract:

Oxygen levels in cancerous tissue can have a significant effect on treatment response: hypoxic tissue is both more radioresistant and more chemoresistant than well-oxygenated tissue. While recent advances in medical imaging have facilitated real-time observation of macroscopic oxygenation, the underlying physics limits the resolution to the millimetre domain, whereas oxygen tension varies over a micrometre scale. If the distribution of oxygen in the tumour micro-environment can be accurately ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1098/rsos.140080

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Institute
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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
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Funding agency for:
Grimes, DR
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Funding agency for:
Partridge, M
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Publisher:
Royal Society Publisher's website
Journal:
Royal Society open science Journal website
Volume:
1
Issue:
1
Pages:
140080
Publication date:
2014
DOI:
EISSN:
2054-5703
URN:
uuid:770cdd67-3447-4b72-a3ef-ec1cd4d85e32
Source identifiers:
527112
Local pid:
pubs:527112
Language:
English
Keywords:

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