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Genomic organization and chromosomal localization of a member of the MAP kinase phosphatase gene family to human chromosome 11p15.5 and a pseudogene to 10q11.2.

Abstract:

Mitogen-activated protein kinase phosphatases (MKPs) play a central role in a variety of signaling pathways. We recently described a novel murine MKP, M3/6, which is uniquely specific for c-Jun N-terminal kinase/stress-activated protein kinase and p38 kinase. Here we report the localization of the human orthologue of this gene, HB5, to within 150 kb of H19 on human chromosome 11p15.5. The gene consists of six exons. Two of the introns in HB5 are not found in other genes of this family, sugges...

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Publication status:
Published

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Publisher copy:
10.1006/geno.1997.4737

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
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Journal:
Genomics
Volume:
42
Issue:
2
Pages:
284-294
Publication date:
1997-06-05
DOI:
EISSN:
1089-8646
ISSN:
0888-7543
URN:
uuid:76e852db-3987-45ca-8d90-771106136932
Source identifiers:
29605
Local pid:
pubs:29605

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