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Journal article

Aetiopathogenesis of primary sclerosing cholangitis.

Abstract:

The aetiology and pathogenesis of PSC have not yet been clearly defined. The hypothesis that PSC is an immune mediated disease is supported by associations with HLA haplotypes, the presence of autoantibodies, increased levels of total serum immunoglobulins and the association with other autoimmune diseases. PSC does not, however, have many of the characteristics of classical autoimmunity, particularly the usual female preponderance of disease and lack of a good response to immunosuppression. ...

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Publication status:
Published

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Publisher copy:
10.1053/bega.2001.0206

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Best practice and research. Clinical gastroenterology
Volume:
15
Issue:
4
Pages:
577-589
Publication date:
2001-08-01
DOI:
EISSN:
1532-1916
ISSN:
1521-6918
Source identifiers:
171671
Language:
English
Keywords:
Pubs id:
pubs:171671
UUID:
uuid:76e3fff5-7763-4a00-a6ab-07b8604560b7
Local pid:
pubs:171671
Deposit date:
2012-12-19

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