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Journal article

Sensorimotor adaptation as a behavioural biomarker of early spinocerebellar ataxia type 6

Abstract:

Early detection of the behavioural deficits of neurodegenerative diseases may help to describe the pathogenesis of such diseases and establish important biomarkers of disease progression. The aim of this study was to identify how sensorimotor adaptation of the upper limb, a cerebellar-dependent process restoring movement accuracy after introduction of a perturbation, is affected at the pre-clinical and clinical stages of spinocerebellar ataxia type 6 (SCA6), an inherited neurodegenerative dis...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41598-017-02469-7

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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More from this funder
Funding agency for:
Benitez-Riveiro, S
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Funding agency for:
Butler, C
Grant:
Clinician Scientist fellowship (MR/K010395/1)
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Publisher:
Springer Nature Publisher's website
Journal:
Scientific Reports Journal website
Volume:
7
Pages:
2366
Publication date:
2017-05-24
Acceptance date:
2017-04-11
DOI:
EISSN:
2045-2322
ISSN:
2045-2322
Source identifiers:
697364
Pubs id:
pubs:697364
UUID:
uuid:76e22055-7289-402d-a3be-96d25dc3f084
Local pid:
pubs:697364
Deposit date:
2017-05-26

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