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The mechanisms of parasite clearance after antimalarial treatment of Plasmodium falciparum malaria.

Abstract:

Studies were conducted to determine how malaria parasites are cleared from the blood after antimalarial treatment. Neither artesunate nor quinine decreased parasitized red cell deformability or increased antibody binding. In acute falciparum malaria, ring-infected erythrocyte surface antigen (RESA) was observed in erythrocytes without malaria parasites (RESA-red blood cell [RBC]), indicating prior parasitization. In uncomplicated malaria, RESA-RBC numbers increased significantly (P=.002) with...

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Publication status:
Published

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Publisher copy:
10.1086/315718

Authors


Chotivanich, K More by this author
Udomsangpetch, R More by this author
Dondorp, A More by this author
Williams, T More by this author
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Volume:
182
Issue:
2
Pages:
629-633
Publication date:
2000-08-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:76d6ec22-50d0-475d-8c16-260fb8e4e4d4
Source identifiers:
15721
Local pid:
pubs:15721

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