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Deterioration of physical performance and cognitive function in rats with short-term high-fat feeding

Abstract:

Efficiency, defined as the amount of work produced for a given amount of oxygen consumed, is a key determinant of endurance capacity, and can be altered by metabolic substrate supply, in that fatty acid oxidation is less efficient than glucose oxidation. It is unclear, however, whether consumption of a high-fat diet would be detrimental or beneficial for endurance capacity, due to purported glycogen-sparing properties. In addition, a high-fat diet over several months leads to cognitive impair...

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Publication status:
Published

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Publisher copy:
10.1096/fj.09-139691

Authors


Murray, AJ More by this author
Knight, NS More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
McAleese, S More by this author
Deacon, RMJ More by this author
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Journal:
FASEB JOURNAL
Volume:
23
Issue:
12
Pages:
4353-4360
Publication date:
2009-12-05
DOI:
EISSN:
1530-6860
ISSN:
0892-6638
URN:
uuid:76d41df5-898d-42f2-a87f-be9538303d59
Source identifiers:
106834
Local pid:
pubs:106834
Language:
English
Keywords:

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