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Journal article

Survival in MS: a randomized cohort study 21 years after the start of the pivotal IFNβ-1b trial.

Abstract:

OBJECTIVE: To examine the effects of interferon beta (IFNβ)-1b on all-cause mortality over 21 years in the cohort of 372 patients who participated in the pivotal randomized clinical trial (RCT), retaining (in the analysis) the original randomized treatment-assignments. METHODS: For this randomized long-term cohort study, the primary outcome, defined before data collection, was the comparison of all-cause mortality between the IFNβ-1b 250 μg and placebo groups from the time of randomization t...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, WTC Human Genetics
Role:
Author
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Journal:
Neurology
Volume:
78
Issue:
17
Pages:
1315-1322
Publication date:
2012-04-05
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
URN:
uuid:76c66393-5ea5-4c08-bc6e-b94ee0ce7e5a
Source identifiers:
322718
Local pid:
pubs:322718

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