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Correlations of interictal FDG-PET metabolism and ictal SPECT perfusion changes in human temporal lobe epilepsy with hippocampal sclerosis.

Abstract:

BACKGROUND: The pathophysiological role of the extensive interictal cerebral hypometabolism in complex partial seizures (CPS) in refractory mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) is poorly understood. Our aim was to study ictal-interictal SPECT perfusion versus interictal fluorodeoxyglucose (FDG)-PET metabolic patterns. METHODS: Eleven adults with refractory unilateral mTLE-HS, who were rendered seizure free after epilepsy surgery, were included. All had an interic...

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Van Paesschen, W More by this author
Van Laere, K More by this author
Palmini, A More by this author
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Journal:
NeuroImage
Volume:
32
Issue:
2
Pages:
684-695
Publication date:
2006-08-05
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
URN:
uuid:76c52933-2fb8-4df0-a73a-46930a7c202a
Source identifiers:
429459
Local pid:
pubs:429459

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