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Characterization of short tandem repeats from thirty-one human telomeres.

Abstract:

Completion of genetic and physical maps requires markers from the ends (telomeres) of every human chromosome. We have searched for short tandem repeats (microsatellites) in cosmid and P1 clones and generated 661 sequence-tagged sites (STS) from the terminal 300 kb of 31 human chromosome ends. PCR assays were successfully designed for 58 microsatellites and mapped both genetically and on radiation hybrids (RHs) to confirm their telomeric location. Sequence analysis revealed marked variation in...

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Publication status:
Published

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Authors


Rosenberg, M More by this author
Nusbaum, HC More by this author
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Journal:
Genome research
Volume:
7
Issue:
9
Pages:
917-923
Publication date:
1997-09-05
EISSN:
1549-5469
ISSN:
1088-9051
URN:
uuid:76bd5446-6bdb-45c7-8f63-9680d37d0c60
Source identifiers:
45672
Local pid:
pubs:45672

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