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The Role of the Immune System in Cutaneous Squamous Cell Carcinoma.

Abstract:

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer. In immunosuppressed populations it is a source of considerable morbidity and mortality due to its enhanced recurrence and metastatic potential. In common with many malignancies, leucocyte populations are both protective against cancer development and also play a role in 'sculpting' the nascent tumor, leading to loss of immunogenicity and tumor progression. UV radiation and chronic viral carriage may represent uniq...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.3390/ijms20082009

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine; Surgical Sciences
Role:
Author
ORCID:
0000-0001-5793-4777
More by this author
Role:
Author
ORCID:
0000-0002-6644-0979
Publisher:
MDPI Publisher's website
Journal:
International Journal of Molecular Sciences Journal website
Volume:
20
Issue:
8
Pages:
Article: 2009
Publication date:
2019-04-24
Acceptance date:
2019-04-19
DOI:
EISSN:
1422-0067
ISSN:
1661-6596
Pubs id:
pubs:995447
URN:
uri:76a3bd79-ff0c-47a1-a838-fe035a30d249
UUID:
uuid:76a3bd79-ff0c-47a1-a838-fe035a30d249
Local pid:
pubs:995447
Language:
English
Keywords:

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