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Journal article

Focal and diffuse cortical degenerative changes in a marmoset model of multiple sclerosis.

Abstract:

BACKGROUND: Degenerative features, such as neuronal, glial, synaptic and axonal loss, have been identified in neocortical and other grey matter structures in patients with multiple sclerosis, but mechanisms for neurodegeneration are unclear. Cortical demyelinating lesions are a potential cause of this degeneration, but the pathological and clinical significance of these lesions is uncertain as they remain difficult to identify and study in vivo. In this study we aimed to describe and quantify...

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Publication status:
Published

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Publisher copy:
10.1177/1352458509360362

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Multiple sclerosis (Houndmills, Basingstoke, England)
Volume:
16
Issue:
5
Pages:
537-548
Publication date:
2010-05-01
DOI:
EISSN:
1477-0970
ISSN:
1352-4585
Source identifiers:
243703
Language:
English
Keywords:
Pubs id:
pubs:243703
UUID:
uuid:766167e6-35cc-4834-9e79-6e895dc2bb55
Local pid:
pubs:243703
Deposit date:
2012-12-19

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