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Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.

Abstract:

Recent genetic association studies have made progress in uncovering components of the genetic architecture of the body mass index (BMI). We used the ITMAT-Broad-Candidate Gene Association Resource (CARe) (IBC) array comprising up to 49 320 single nucleotide polymorphisms (SNPs) across ~2100 metabolic and cardiovascular-related loci to genotype up to 108 912 individuals of European ancestry (EA), African-Americans, Hispanics and East Asians, from 46 studies, to provide additional insight into ...

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Publisher copy:
10.1093/hmg/dds396

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Journal:
Human molecular genetics
Volume:
22
Issue:
1
Pages:
184-201
Publication date:
2013-01-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:764ec65c-6b9e-4ce7-a493-782270498d2d
Source identifiers:
371380
Local pid:
pubs:371380

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