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Journal article

Proteasome activity imaging and profiling characterizes bacterial effector syringolin A.

Abstract:

Syringolin A (SylA) is a nonribosomal cyclic peptide produced by the bacterial pathogen Pseudomonas syringae pv syringae that can inhibit the eukaryotic proteasome. The proteasome is a multisubunit proteolytic complex that resides in the nucleus and cytoplasm and contains three subunits with different catalytic activities: β1, β2, and β5. Here, we studied how SylA targets the plant proteasome in living cells using activity-based profiling and imaging. We further developed this technology by i...

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Publication status:
Published

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Publisher copy:
10.1104/pp.110.163733

Authors


Kolodziejek, I More by this author
Misas-Villamil, JC More by this author
Kaschani, F More by this author
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Journal:
Plant physiology
Volume:
155
Issue:
1
Pages:
477-489
Publication date:
2011-01-05
DOI:
EISSN:
1532-2548
ISSN:
0032-0889
URN:
uuid:764b08ac-f889-4c08-9da5-c4c2597ae45a
Source identifiers:
411974
Local pid:
pubs:411974

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