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Thesis

Targeting the chemokine signalling pathway using tick saliva peptides

Abstract:

Chemokines are signalling proteins that function to recruit immune cells from the innate and adaptive immune response. Chemokines are classified based on the position of their cysteine residues at the N-terminus as CC, CXC, CX3C or XC (C-cysteine, X-amino acid). Increased expression of chemokines is one of the key findings in a range of inflammatory diseases. Chemokines operate in a network, where multiple chemokines bind a single receptor, and vice versa, and multiple chemokine...

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Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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