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A simple mechanochemical model for calcium signalling in embryonic epithelial cells

Abstract:

Calcium signalling is one of the most important mechanisms of information propagation in the body. In embryogenesis the interplay between calcium signalling and mechanical forces is critical to the healthy development of an embryo but poorly understood. Several types of embryonic cells exhibit calcium-induced contractions and many experiments indicate that calcium signals and contractions are coupled via a two-way mechanochemical feedback mechanism. We present a new analysis of experimental d...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1007/s00285-019-01333-8

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Mathematical Institute
Oxford college:
St Johns College
ORCID:
0000-0002-0146-9164
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Mathematical Institute
Christodoulou, N More by this author
Skourides, PA More by this author
Publisher:
Springer Nature Publisher's website
Journal:
Journal of Mathematical Biology Journal website
Volume:
78
Issue:
7
Pages:
2059–2092
Publication date:
2019-03-02
Acceptance date:
2019-01-30
DOI:
EISSN:
1432-1416
ISSN:
0303-6812
Pubs id:
pubs:966965
URN:
uri:761d62b5-d73a-4213-b503-2c952cafbcd3
UUID:
uuid:761d62b5-d73a-4213-b503-2c952cafbcd3
Local pid:
pubs:966965

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