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Evidence for under-diagnosis of childhood acute lymphoblastic leukaemia in poorer communities within Great Britain

Abstract:

Background: Recorded incidence of childhood acute lymphoblastic leukaemia tends to be lower in poorer communities. A pre-emptive infection hypothesis proposes that some children with leukaemia die from infection without diagnosis of leukaemia. Various different blood abnormalities can occur in untreated leukaemia. Methods: Logistic regression was used to compare pre-treatment blood counts among children aged 1-13 years at recruitment to national clinical trials for acute lymphoblastic leukaem...

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Publisher copy:
10.1038/bjc.2012.102

Authors


Stiller, CA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Mitchell, C More by this author
Carpenter, LM More by this author
Journal:
British Journal of Cancer
Volume:
106
Issue:
9
Pages:
1556-1559
Publication date:
2012-04-24
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:761c89b9-031a-4eb7-b471-0629860cf36e
Source identifiers:
329437
Local pid:
pubs:329437

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