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Effects of gastroprotectant drugs for the prevention and treatment of peptic ulcer disease and its complications: meta-analysis of randomised trials

Abstract:

Background
Gastroprotectant drugs are used for the prevention and treatment of peptic ulcer disease and might reduce its associated complications, but reliable estimates of the effects of gastroprotectants in different clinical settings are scarce. We aimed to examine the effects of proton-pump inhibitors (PPIs), prostaglandin analogues, and histamine-2 receptor antagonists (H2RAs) in different clinical circumstances by doing meta-analyses of tabular data from all rele...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/S2468-1253(18)30037-2

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
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Medical Research Council More from this funder
British Heart Foundation More from this funder
Publisher:
Elsevier: Lancet Publisher's website
Journal:
Lancet Gastroenterology and Hepatology Journal website
Volume:
3
Issue:
4
Pages:
231–241
Publication date:
2018-02-20
Acceptance date:
2018-01-08
DOI:
EISSN:
2468-1253
Pubs id:
pubs:825880
URN:
uri:760c0efe-b4e4-4c09-a388-193f1f0a57fd
UUID:
uuid:760c0efe-b4e4-4c09-a388-193f1f0a57fd
Local pid:
pubs:825880
Paper number:
4

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