- Abstract:
-
The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) has been solved and refined at 2.5 A resolution. The refinement procedure converged at R = 0.181 for all reflections in the range 20.0-2.5 A. In the crystal, the RNA/DNA hybrid duplex has an A' conformation with all but one of the nucleotide sugar moieties adopting a C3'- endo (N) conformation. Both strands in the double helix adopt a global conformation close to the A-form and the width of the minor groove is typical of...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/nar/27.2.555
-
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- Journal:
- Nucleic acids research
- Volume:
- 27
- Issue:
- 2
- Pages:
- 555-561
- Publication date:
- 1999-01-05
- DOI:
- EISSN:
-
1362-4962
- ISSN:
-
0305-1048
- URN:
-
uuid:7608458a-dde6-44b8-b886-646eba44315e
- Source identifiers:
-
400076
- Local pid:
- pubs:400076
- Copyright date:
- 1999
Journal article
The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution.
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