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Journal article

High frequency stimulation of the subthalamic nucleus modulates neuronal activity in the lateral habenula nucleus

Abstract:

High frequency stimulation (HFS) of the subthalamic nucleus (STN) is often used to treat movement disability in advanced Parkinson's disease, but some patients experience debilitating psychiatric effects including depression. Interestingly, HFS of the STN modulates 5-HT neurons in the dorsal raphe nucleus (DRN) which are linked to depression, but the neural substrate of this effect is unknown. Here we tested the effect of STN stimulation on neuronal activity in the lateral habenula nucleus (L...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/ejn.13397

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Hersenstichting Nederland More from this funder
Publisher:
John Wiley & Sons Ltd Publisher's website
Journal:
European Journal of Neuroscience Journal website
Volume:
44
Issue:
9
Pages:
2698–2707
Publication date:
2016-09-13
Acceptance date:
2016-09-10
DOI:
EISSN:
1460-9568
ISSN:
0953-816X
Pmid:
27623306
Source identifiers:
646062
Language:
English
Keywords:
Pubs id:
pubs:646062
UUID:
uuid:75eb1c41-49e9-4d51-8d00-2452696e1041
Local pid:
pubs:646062
Deposit date:
2016-10-06

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