Journal article
Evidence for expression and function of phosphodiesterase type 5 (PDE-V) in rat resistance arteries.
- Abstract:
-
Evidence is provided for expression and a functional role for phosphodiesterase type V (PDE-V) in the rat isolated small mesenteric artery. The reverse transcription polymerase chain reaction (RT--PCR) demonstrated mRNA for PDE-V, while Western blotting and immunocytochemical studies showed corresponding protein expression. Smooth muscle relaxation to the nitric oxide donor, diethylamine NONOate (DEA NONOate; 1 nM - 10 microM; pEC(50)=6.7+/-0.3) was potentiated significantly by the specific i...
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- Publication status:
- Published
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- Publisher copy:
- 10.1038/sj.bjp.0703831
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Authors
Bibliographic Details
- Journal:
- British journal of pharmacology
- Volume:
- 132
- Issue:
- 1
- Pages:
- 13-17
- Publication date:
- 2001-01-01
- DOI:
- EISSN:
-
1476-5381
- ISSN:
-
0007-1188
- Source identifiers:
-
106300
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:106300
- UUID:
-
uuid:75bc79cf-375c-4a29-a847-d1c5b83fcfaf
- Local pid:
- pubs:106300
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2001
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