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Scalable population-level modeling of biological cells incorporating mechanics and kinetics in continuous time

Abstract:

The processes taking place inside the living cell are now understood to the point where predictive computational models can be used to gain detailed understanding of important biological phenomena. A key challenge is to extrapolate this detailed knowledge of the individual cell to be able to explain at the population level how cells interact and respond with each other and their environment. In particular, the goal is to understand how organisms develop, maintain and repair functional tiss...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1098/rsos.180379

Authors


Engblom, S More by this author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Mathematical Institute
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Mathematical Institute
Oxford college:
St Hughs College
ORCID:
0000-0002-6304-9333
Royal Society More from this funder
Publisher:
Royal Society Publisher's website
Journal:
Royal Society Open Science Journal website
Volume:
5
Pages:
180379
Publication date:
2018-08-01
Acceptance date:
2018-04-30
DOI:
EISSN:
2054-5703
Pubs id:
pubs:853627
URN:
uri:759612a3-1054-4c13-b73a-f5b3ebc6db50
UUID:
uuid:759612a3-1054-4c13-b73a-f5b3ebc6db50
Local pid:
pubs:853627

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