- Abstract:
-
We tested the efficacy and safety of chlorproguanil/dapsone co-administered with artesunate (CD+A) for the treatment of uncomplicated Plasmodium falciparum malaria in children compared with amodiaquine+sulfadoxine/pyrimethamine (AQ+SP) at two different sites in Rwanda. The trial was open label and 800 patients were randomly assigned to AQ+SP (n=400) or CD+A (n=400). Patients were hospitalised for 3 days and then followed-up weekly until Day 28 after treatment. Clinical and parasitological out...
Expand abstract - Publisher copy:
- 10.1016/j.trstmh.2008.01.013
-
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- Journal:
- Transactions of the Royal Society of Tropical Medicine and Hygiene
- Volume:
- 102
- Issue:
- 5
- Pages:
- 412-420
- Publication date:
- 2008-05-05
- DOI:
- EISSN:
-
1878-3503
- ISSN:
-
0035-9203
- URN:
-
uuid:7592c6bc-b79f-4be3-a076-55d718ac576d
- Source identifiers:
-
290336
- Local pid:
- pubs:290336
- Copyright date:
- 2008
Journal article
A randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malaria.
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