Journal article icon

Journal article

A randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malaria.

Abstract:

We tested the efficacy and safety of chlorproguanil/dapsone co-administered with artesunate (CD+A) for the treatment of uncomplicated Plasmodium falciparum malaria in children compared with amodiaquine+sulfadoxine/pyrimethamine (AQ+SP) at two different sites in Rwanda. The trial was open label and 800 patients were randomly assigned to AQ+SP (n=400) or CD+A (n=400). Patients were hospitalised for 3 days and then followed-up weekly until Day 28 after treatment. Clinical and parasitological out...

Expand abstract

Actions


Access Document


Authors


Fanello, CI More by this author
Ngamije, D More by this author
Uwimana, A More by this author
Ndahindwa, V More by this author
Expand authors...
Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume:
102
Issue:
5
Pages:
412-420
Publication date:
2008-05-05
DOI:
EISSN:
1878-3503
ISSN:
0035-9203
URN:
uuid:7592c6bc-b79f-4be3-a076-55d718ac576d
Source identifiers:
290336
Local pid:
pubs:290336

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP