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Journal article

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma.

Abstract:

Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We conducted a genome-wide association study including 1,854 PACG cases and 9,608 controls across 5 sample collections in Asia. Replication experiments were conducted in 1,917 PACG cases and 8,943 controls collected from a further 6 sample collections. We report significant associations at three new loci: rs11024102 in PLEKHA7 (per-allele odds ratio (OR)=1.22; P=5.33×10(-12)), rs3753841 in COL11A1 (per-allele OR=1....

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Publication status:
Published

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Publisher copy:
10.1038/ng.2390

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Journal:
Nature genetics
Volume:
44
Issue:
10
Pages:
1142-1146
Publication date:
2012-10-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:756f0362-beac-4c5c-bf43-1a0740ba194a
Source identifiers:
349953
Local pid:
pubs:349953

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