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Thesis

Mechanisms of Non-Progressing Paediatric HIV-1 Infection

Abstract:

HIV-infected children progress more rapidly to AIDS than adults and, in sub-Saharan Africa, without antiretroviral therapy (ART), more than 50% will die before their second birthday. However, a minority of perinatally infected children will become paediatric non-progressors (PNP). The reasons for this rapid disease progression and the immunological correlates of protection against rapid progression are incompletely understood. This thesis focuses principally on paediatric HIV in...

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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