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Thesis

Factors controlling the pluripotent state of human embryonic stem cells

Abstract:

In the field of regenerative medicine, human embryonic stem (hES) cells offer the potential to treat degenerative diseases and replace damaged or non-functional tissue. However, it is not fully clear how hES cells retain a pluripotent state or differentiate into specific cell lineages. Although most of previous research has found that various proteins are responsible for the balance in hES cell maintenance and differentiation, there is mounting evidence for non-coding RNAs as important pla...

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Supervisor
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Funding agency for:
Maria del Pilar Vazquez Arango
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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