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Genome-wide analysis of mutations in mutant lineages selected following fast-neutron irradiation mutagenesis of Arabidopsis thaliana.

Abstract:

Ionizing radiation has long been known to induce heritable mutagenic change in DNA sequence. However, the genome-wide effect of radiation is not well understood. Here we report the molecular properties and frequency of mutations in phenotypically selected mutant lines isolated following exposure of the genetic model flowering plant Arabidopsis thaliana to fast neutrons (FNs). Previous studies suggested that FNs predominantly induce deletions longer than a kilobase in A. thaliana. However, we ...

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Publication status:
Published

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Publisher copy:
10.1101/gr.131474.111

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Institution:
University of Oxford
Department:
Oxford
Role:
Author
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Journal:
Genome research
Volume:
22
Issue:
7
Pages:
1306-1315
Publication date:
2012-07-05
DOI:
EISSN:
1549-5469
ISSN:
1088-9051
URN:
uuid:75394961-ef1e-4cca-832d-eff761d61d13
Source identifiers:
323074
Local pid:
pubs:323074

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