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Enhancement of microbubble mediated gene delivery by simultaneous exposure to ultrasonic and magnetic fields.

Abstract:

It has been shown in previous studies that gene delivery can be enhanced by a variety of minimally-invasive techniques including: (1) exposure of cells to ultrasound in the presence of DNA and gas microbubbles and (2) exposure of cells to a magnetic field in the presence of DNA conjugated to magnetic nanoparticles. The aim of this work was to investigate whether it was possible to combine the advantages of both these techniques. It was found that transfection of Chinese hamster ovary cells by...

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Role:
Author
Journal:
Ultrasound in medicine and biology
Volume:
35
Issue:
5
Pages:
861-868
Publication date:
2009-05-05
DOI:
EISSN:
1879-291X
ISSN:
0301-5629
URN:
uuid:75295ca2-9b02-4cbf-ac4c-594aa61a6eca
Source identifiers:
327734
Local pid:
pubs:327734

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