Journal article
High-resolution analysis of epigenetic changes associated with X inactivation.
- Abstract:
-
Differentiation of female murine ES cells triggers silencing of one X chromosome through X-chromosome inactivation (XCI). Immunofluorescence studies showed that soon after Xist RNA coating the inactive X (Xi) undergoes many heterochromatic changes, including the acquisition of H3K27me3. However, the mechanisms that lead to the establishment of heterochromatin remain unclear. We first analyze chromatin changes by ChIP-chip, as well as RNA expression, around the X-inactivation center (Xic) in f...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Genome research
- Volume:
- 19
- Issue:
- 8
- Pages:
- 1361-1373
- Publication date:
- 2009-08-01
- DOI:
- EISSN:
-
1549-5469
- ISSN:
-
1088-9051
- Source identifiers:
-
100042
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:100042
- UUID:
-
uuid:751b604e-2812-4c94-ac9d-dc6472de2a36
- Local pid:
- pubs:100042
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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