Gamma knife radiosurgery: a safe and effective salvage treatment for pituitary tumours not controlled despite conventional radiotherapy.

Journal article

OBJECTIVE: We report the use of 'gamma knife' (GK) radiosurgery in 25 patients with pituitary adenomas not cured despite conventional therapy, including external beam radiotherapy. PATIENTS AND METHODS: All patients had previously received conventional radiotherapy for a mean of 11.8 years prior to receiving GK; 23 out of 25 had also undergone pituitary surgery on at least one occasion. Seventeen had hyperfunctioning adenomas that still required medical therapy without an adequate biochemica...

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Authors: Swords, F; Monson, J; Besser, G; Chew, S; Drake, WM

• Publication status: Published
• Journal: European journal of endocrinology / European Federation of Endocrine Societies
• Volume: 161
• Issue: 6
• Pages: 819-828
• Publication date: 2009-12-01
• DOI: 10.1530/eje-09-0493
• EISSN: 1479-683X
• ISSN: 0804-4643
• Language: English
• Keywords: Pituitary Neoplasms; Female; Adenoma; Adult; Middle Aged; Male; Treatment Outcome; Insulin-Like Growth Factor I; Aged; Humans; Growth Hormone-Secreting Pituitary Adenoma; Radiosurgery; Human Growth Hormone; Prolactinoma; ACTH-Secreting Pituitary Adenoma