- Abstract:
-
Diverse classes of noncoding RNA, including small nuclear RNAs (snRNAs), play fundamental regulatory roles at many stages of gene expression. For example, recent studies have implicated 7SK RNA and components of the splicing apparatus in the regulation of transcriptional elongation. Here we present the first evidence of the involvement of an snRNA in the regulation of transcriptional initiation. We demonstrate that TFIIH, a general transcription initiation factor, specifically associates with...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/nsb862
-
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- Journal:
- Nature structural biology
- Volume:
- 9
- Issue:
- 11
- Pages:
- 800-805
- Publication date:
- 2002-11-05
- DOI:
- ISSN:
-
1072-8368
- URN:
-
uuid:74bfefb3-53df-4659-8d85-acdc7aa786ed
- Source identifiers:
-
5080
- Local pid:
- pubs:5080
- Copyright date:
- 2002
Journal article
U1 snRNA associates with TFIIH and regulates transcriptional initiation.
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