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Journal article

Statins and bone: myth or reality?

Abstract:

In the space of a few weeks, four articles appeared in the The Lancet and JAMA suggesting that using 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors (statins) is associated with increased bone mineral density (BMD) and a reduced fracture risk. The stimulus for these case-control studies came from reports that the statins have unexpected effects on bone, increasing bone formation in rodents. These observations offered a new insight into the potential importance of the chol...

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Publication status:
Published

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Publisher copy:
10.1007/s00223-001-2017-7

Authors


Edwards, CJ More by this author
Russell, RG More by this author
Spector, TD More by this author
Journal:
Calcified tissue international
Volume:
69
Issue:
2
Pages:
63-66
Publication date:
2001-08-05
DOI:
EISSN:
1432-0827
ISSN:
0171-967X
URN:
uuid:74a9892e-f1f4-43ba-8eca-251d3245944b
Source identifiers:
109316
Local pid:
pubs:109316

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