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Osteomalacia as a late metabolic complication of Ifosfamide chemotherapy in young adults: illustrative cases and review of the literature.

Abstract:

Purpose. Ifosfamide is a drug commonly used in the management of sarcomas and other solid tumours. One potential toxicity of its use is renal tubular damage, which can lead to skeletal abnormalities; rickets in children and osteomalacia in adults. We aimed to characterise this rare complication in adults. Patients. Three illustrative patient cases treated in our institution are presented. All were treated for sarcoma, and received varying doses of ifosfamide during their therapy. Methods. We ...

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Publisher copy:
10.1155/2007/91586

Authors


Church, DN More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology
Harper, SJ More by this author
Wakeley, CJ More by this author
Journal:
Sarcoma
Volume:
2007
Pages:
91586
Publication date:
2007
DOI:
EISSN:
1369-1643
ISSN:
1357-714X
URN:
uuid:749fc932-a890-4f68-abb8-86a14fb36d56
Source identifiers:
247847
Local pid:
pubs:247847
Language:
English

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