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Dietary fatty acids make a rapid and substantial contribution to VLDL-triacylglycerol in the fed state.

Abstract:

Exaggerated postprandial lipemia is associated with coronary heart disease and type II diabetes, yet few studies have examined the effect of sequential meals on lipoprotein metabolism. We have used 13C-labeled fatty acids to trace the incorporation of fatty acid derived from a meal into apolipoprotein B-100 (apoB-100)-containing lipoproteins and plasma nonesterified fatty acids (NEFA) following two consecutive meals. Healthy volunteers (n=8) were given breakfast labeled with [1-(13)C]palmitic...

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Publication status:
Published

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Publisher copy:
10.1152/ajpendo.00409.2006

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Burdge, GC More by this author
Wootton, SA More by this author
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Journal:
American journal of physiology. Endocrinology and metabolism
Volume:
292
Issue:
3
Pages:
E732-E739
Publication date:
2007-03-05
DOI:
EISSN:
1522-1555
ISSN:
0193-1849
URN:
uuid:74800373-09f4-43a8-9e48-4ae69b3eb305
Source identifiers:
15431
Local pid:
pubs:15431

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