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A molecular dynamics study of the vascular endothelial glycocalyx layer

Abstract:

The luminal surface of endothelial cells which line the vasculature is coated with a layer of membrane-bound macromolecules of a mixed carbohydrate and protein nature, collectively described as a glycocalyx, from the greek meaning "sweethusk/covering". Experiments have consistently revealed the pivotal role of the endothelial glycocalyx layer in vasoregulation and the layer's contribution to mechanotransduction pathways. However, the exact mechanism by which the glycocalyx mediates and in...

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Division:
MPLS
Department:
Engineering Science
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Alexander S. Onassis Public Benefit Foundation More from this funder
State Scholarships Foundation of Greece (IKY) More from this funder
RCUK Digital Economy More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:7473df16-4c96-443a-b69c-24a921ba5f42
Deposit date:
2017-06-20

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