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Mef2c is activated directly by Ets transcription factors through an evolutionarily conserved endothelial cell-specific enhancer.

Abstract:

Members of the Myocyte Enhancer Factor 2 (MEF2) family of transcription factors play key roles in the development and differentiation of numerous cell types during mammalian development, including the vascular endothelium. Mef2c is expressed very early in the development of the endothelium, and genetic studies in mice have demonstrated that mef2c is required for vascular development. However, the transcriptional pathways involving MEF2C during endothelial cell development have not been define...

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Publication status:
Published

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Publisher copy:
10.1016/j.ydbio.2004.08.016

Authors


Anderson, JP More by this author
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Journal:
Developmental biology
Volume:
275
Issue:
2
Pages:
424-434
Publication date:
2004-11-05
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
URN:
uuid:745e85fd-19f1-4407-8f20-c229fa015902
Source identifiers:
68224
Local pid:
pubs:68224

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