Journal article
From Parkinsonian thalamic activity to restoring thalamic relay using deep brain stimulation: new insights from computational modeling.
- Abstract:
-
We present a computational model of a thalamocortical relay neuron for exploring basal ganglia thalamocortical loop behavior in relation to Parkinson's disease and deep brain stimulation (DBS). Previous microelectrode, single-unit recording studies demonstrated that oscillatory interaction within and between basal ganglia nuclei is very often accompanied by synchronization at Parkinsonian rest tremor frequencies (3-10 Hz). These oscillations have a profound influence on thalamic projections a...
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- Publisher copy:
- 10.1088/1741-2560/8/6/066005
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Bibliographic Details
- Journal:
- Journal of neural engineering
- Volume:
- 8
- Issue:
- 6
- Pages:
- 066005
- Publication date:
- 2011-12-05
- DOI:
- EISSN:
-
1741-2552
- ISSN:
-
1741-2560
- URN:
-
uuid:7432c44e-de74-4077-a160-f8f793543336
- Source identifiers:
-
266850
- Local pid:
- pubs:266850
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2011
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