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Opa protein repertoires of disease-causing and carried meningococci

Abstract:

The meningococcal Opa proteins play an important role in pathogenesis by mediating invasion of human cells. The aim of this investigation was to determine whether carried and disease-associated meningococci possess different Opa repertoires and whether the diversity of these proteins is associated with clinical severity of disease. Opa repertoires in 227 disease-associated meningococci, isolated in the United Kingdom over a period of 6 years, were compared to the repertoires in 190 asymptomat...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/jcm.00005-08

Authors


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Institution:
University of Oxford
Department:
MSD, Department of Paediatrics
More by this author
Institution:
University of Oxford
Department:
MPLSD, Department of Zoology
More by this author
Institution:
University of Oxford
Department:
MPLSD, Department of Zoology
More by this author
Institution:
University of Oxford
Department:
MPLSD, Department of Zoology
More by this author
Institution:
University of Oxford
Department:
MPLSD, Department of Zoology
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Meningitis Research Foundation More from this funder
Publisher:
American Society for Microbiology Publisher's website
Journal:
Journal of Clinical Microbiology Journal website
Volume:
46
Issue:
9
Pages:
3033-3041
Publication date:
2008-09-05
DOI:
EISSN:
1098-660X
ISSN:
0095-1137
URN:
uuid:7431f0f0-e622-49ad-8ca5-2e5f45483693
Source identifiers:
119171
Local pid:
pubs:119171

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