Journal article
Regulation of hypoxia-induced cell death in human tenocytes.
- Abstract:
-
Degenerate shoulder tendons display evidence of hypoxia. However tendons are relatively avascular and not considered to have high oxygen requirements and the vulnerability of tendon cells to hypoxia is unclear. Cultured human tenocytes were exposed to hypoxia and the cellular response detected using QPCR, Western blotting, viability, and ELISA assays. We find that tenocytes respond to hypoxia in vitro by activating classical HIF-1α-driven pathways. Total hypoxia caused significant tenocyte ap...
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- Publisher copy:
- 10.1155/2012/984950
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Authors
Bibliographic Details
- Journal:
- Advances in orthopedics
- Volume:
- 2012
- Pages:
- 984950
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
-
2090-3472
- ISSN:
-
2090-3464
- Source identifiers:
-
374243
Item Description
- Language:
- English
- Pubs id:
-
pubs:374243
- UUID:
-
uuid:741bc3d9-cf99-4b7b-8289-66707824e339
- Local pid:
- pubs:374243
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2012
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