Journal article
Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease.
- Abstract:
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BACKGROUND: There is evidence that iron may play a role in the pathology of Alzheimer's disease (AD). There may be genetic factors that contribute to iron deposition resulting in tissue damage thus exacerbating AD. METHODS: We have genotyped 269 healthy elderly controls, 191 cases with definite or probable AD, and 69 with mild cognitive impairment (MCI) from the OPTIMA cohort. RESULTS: We have examined the interaction between the C2 variant of the transferrin (TF) gene and the C282Y allele of...
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- Publication status:
- Published
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- Publisher copy:
- 10.1136/jmg.2003.015552
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Authors
Bibliographic Details
- Journal:
- Journal of medical genetics
- Volume:
- 41
- Issue:
- 4
- Pages:
- 261-265
- Publication date:
- 2004-04-01
- DOI:
- EISSN:
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1468-6244
- ISSN:
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0022-2593
- Source identifiers:
-
195483
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:195483
- UUID:
-
uuid:74197fcd-ee7a-48ce-b38f-ae17e65cdf06
- Local pid:
- pubs:195483
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2004
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