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Stimulation of the subthalamic nucleus improves velocity of ballistic movements in Parkinson's disease.

Abstract:

High-frequency stimulation of the subthalamic nucleus can markedly improve motor function in patients with Parkinson's disease. However, the underlying mechanisms mediating these improvements are not well understood. In particular, whether motor function is differentially improved in distal or proximal movements is not fully determined. Also, whether reaction time is improved along with other motor parameters is still a matter of debate. Here, we test patients OFF and ON subthalamic nucleus s...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
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Journal:
Neuroreport
Volume:
23
Issue:
6
Pages:
390-394
Publication date:
2012-04-05
DOI:
EISSN:
1473-558X
ISSN:
0959-4965
URN:
uuid:73d29d56-a54c-4d70-95f3-d0f4ab2bf7e3
Source identifiers:
316230
Local pid:
pubs:316230

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