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Carbohydrate binding molecules in malaria pathology.

Abstract:

Interactions between parasite-encoded proteins and host carbohydrate molecules are essential at multiple stages in the life cycle of the malaria-causing parasite, Plasmodium falciparum, and these interactions are targets for the development of therapeutics to treat the disease. Here we review recent structural studies of carbohydrate binding modules that mediate recognition events important for cell invasion and cytoadhesion. In particular we focus on the structures of two molecules; the eryt...

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Publication status:
Published

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Publisher copy:
10.1016/j.sbi.2010.06.008

Authors


Higgins, MK More by this author
Journal:
Current opinion in structural biology
Volume:
20
Issue:
5
Pages:
560-566
Publication date:
2010-10-05
DOI:
EISSN:
1879-033X
ISSN:
0959-440X
URN:
uuid:73cc11e0-d237-4470-bc2b-e5dd583dffdb
Source identifiers:
196850
Local pid:
pubs:196850

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