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Journal article

Two color imaging of different hypoxia levels in cancer cells

Abstract:

Hypoxia (low oxygen levels) occurs in a range of biological contexts, including plants, bacterial biofilms, and solid tumors; it elicits responses from these biological systems that impact their survival. For example, conditions of low oxygen make treating tumors more difficult and have a negative impact on patient prognosis. Therefore, chemical probes that enable the study of biological hypoxia are valuable tools to increase the understanding of disease-related conditions that involve low ox...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1021/jacs.2c12493

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Chemistry Research Laboratory
Role:
Author
ORCID:
0000-0003-1878-5857
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Sub department:
CRUK/MRC Ox Inst for Radiation Oncology
Role:
Author
ORCID:
0000-0002-2335-3146
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Research group:
Chemistry Research Laboratory
Oxford college:
St Hugh's College
Role:
Author
ORCID:
0000-0002-5148-117X
Publisher:
American Chemical Society
Journal:
Journal of the American Chemical Society More from this journal
Volume:
145
Issue:
4
Pages:
2572–2583
Publication date:
2023-01-19
Acceptance date:
2023-01-19
DOI:
EISSN:
1520-5126
ISSN:
0002-7863
Language:
English
Keywords:
Pubs id:
1324738
Local pid:
pubs:1324738
Deposit date:
2023-01-21

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