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Short communication: preclinical evaluation of candidate HIV type 1 vaccines in inbred strains and an outbred stock of mice.

Abstract:

Outstanding animal immunogenicity is a prerequisite for progression of novel vaccines to clinical trials. The measurement of vaccine immunogenicity is critically dependent on the specificity, accuracy, sensitivity, and precision of the employed assays. This has been greatly aided by the generation of isogenic mouse strains. Here, we identified three novel H-2(d) -restricted CD8+ T cell epitopes derived from the human immunodeficiency virus type 1 and demonstrated a fine evaluation of the vacc...

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Publication status:
Published

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Publisher copy:
10.1089/aid.2007.0009

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Journal:
AIDS research and human retroviruses
Volume:
23
Issue:
7
Pages:
857-862
Publication date:
2007-07-05
DOI:
EISSN:
1931-8405
ISSN:
0889-2229
URN:
uuid:738c6d7c-1253-41b4-8a77-75870e21b915
Source identifiers:
67004
Local pid:
pubs:67004

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