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Central role of JC virus-specific CD4+ lymphocytes in progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome.

Abstract:

Progressive multi-focal leucoencephalopathy and progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome are caused by infection of the central nervous system with the JC polyoma virus. Both are complications of monoclonal antibody therapy in multiple sclerosis and other autoimmune diseases. Progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome can obscure the diagnosis of progressive multi-focal leucoencephalopathy and lead to ...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awr206

Authors


Schippling, S More by this author
Breiden, P More by this author
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Journal:
Brain : a journal of neurology
Volume:
134
Issue:
Pt 9
Pages:
2687-2702
Publication date:
2011-09-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:738826a0-169a-481a-92a7-8ab058aa4e2f
Source identifiers:
179976
Local pid:
pubs:179976

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