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Interobserver variability in histologic evaluation of liver fibrosis using categorical and quantitative scores

Abstract:

Objectives: The aim of the study was to investigate the interobserver agreement for categorical and quantitative scores of liver fibrosis. Methods: Sixty-five consecutive biopsy specimens from patients with mixed liver disease etiologies were assessed by three pathologists using the Ishak and nonalcoholic steatohepatitis Clinical Research Network (NASH CRN) scoring systems, and the fibrosis area (collagen proportionate area [CPA]) was estimated by visual inspection (visual-CPA). A subset of 2...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/ajcp/aqx011

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Role:
Author
Publisher:
Oxford University Press
Journal:
American Journal of Clinical Pathology More from this journal
Volume:
147
Issue:
4
Pages:
364-369
Publication date:
2017-03-15
DOI:
EISSN:
1943-7722
ISSN:
0002-9173
Language:
English
Keywords:
Pubs id:
pubs:687701
UUID:
uuid:7385d230-5761-4ad6-a7a7-4952fd962c41
Local pid:
pubs:687701
Source identifiers:
687701
Deposit date:
2017-05-02

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