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Antigen-non-specific T-cell factor in B-cell activation. Origin, biological properties and failure to show a relationship to H-2.

Abstract:

A population of T cells sensitive to ALS treatment release a non-specific factor (NSF) capable of replacing T cells in the response of nude spleen cells to erythrocyte antigens. This factor cannot be removed by immunoadsorbents with specificities directed towards products of the H2 complex, nor by lentil lectin, unlike certain specific T-cell factors. Furthermore, it functions across histocompatibility differences between mouse strains. It has been directly demonstrated that this factor can i...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Immunology
Volume:
30
Issue:
5
Pages:
723-733
Publication date:
1976-05-05
EISSN:
1365-2567
ISSN:
0019-2805
URN:
uuid:737ff14b-439f-44a0-86e4-2b22b7bade45
Source identifiers:
29840
Local pid:
pubs:29840

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