- Abstract:
-
OBJECTIVES: Results from recent drug trials suggest a role for the cholinergic system in the manifestation of neuropsychiatric symptoms in AD. To date, the status of muscarinic acetylcholine receptor subtypes in AD in relation to accompanying behavioral disturbances is unknown. This study aimed to measure alterations of muscarinic M(1) and M(2) receptor binding in the frontal and temporal cortex of AD and to correlate the neurochemical findings with clinical features. METHODS: The cognitive a...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1212/wnl.57.5.805
-
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- Journal:
- Neurology
- Volume:
- 57
- Issue:
- 5
- Pages:
- 805-811
- Publication date:
- 2001-09-05
- DOI:
- EISSN:
-
1526-632X
- ISSN:
-
0028-3878
- URN:
-
uuid:7363a688-782e-4d48-9940-70bca8bc3f6f
- Source identifiers:
-
242408
- Local pid:
- pubs:242408
- Copyright date:
- 2001
Journal article
Psychosis of Alzheimer's disease is associated with elevated muscarinic M2 binding in the cortex.
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