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Journal article

Short, tin-free synthesis of all three inthomycins

Abstract:
The inthomycins are a family of structurally and biologically rich natural products isolated from Streptomyces species. Herein the implementation of a modular synthetic route is reported that has enabled the enantioselective synthesis of all three inthomycins. Key steps include Suzuki and Sonogashira cross-couplings and an enantioselective Kiyooka aldol reaction.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/chem.201803794

Authors


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Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Oxford college:
Somerville College
Role:
Author
ORCID:
0000-0002-5181-5301
Publisher:
Wiley Publisher's website
Journal:
Chemistry - A European Journal Journal website
Volume:
24
Issue:
63
Pages:
16753-16756
Publication date:
2018-10-10
Acceptance date:
2018-08-27
DOI:
EISSN:
1521-3765
ISSN:
0947-6539
Pmid:
30338587
Source identifiers:
936553
Language:
English
Pubs id:
pubs:936553
UUID:
uuid:7357d084-b48d-43fa-8da8-d8cc132f6e89
Local pid:
pubs:936553
Deposit date:
2018-12-20

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